Powered by:

The mission of the Vanderbilt Center for Stem Cell Biology is to learn more about the biology of stem cells and mechanisms for directing their differentiation to specific cell fates.

Embryonic stem cells are able to differentiate into any of the many different cell types found in the body. A great deal remains to be learned about them, and how to convert them into various tissue and cell types that can be used to treat a variety of human diseases.

The Vanderbilt Center for Stem Cell Biology is home for the Coordinating Center for the Beta Cell Biology Consortium. A major goal of this consortium of scientists is to learn how to make pancreatic beta cells, which are destroyed in Type 1 diabetes, from embryonic stem cells.

Faculty

Scott Baldwin, M.D.
Faculty Member
Member since 2009
Aaron Bowman, Ph.D.
Faculty Member
Member since 2009
Robert Coffey, MD
Faculty Member
Member since 2010
Mark de Caestecker, M.B., B.S., Ph.D.,
Faculty Member
Member since 2010
Kevin Ess, M.D., Ph.D.
Faculty Member
Member since 2009
Maureen Gannon, PhD
Faculty Member
Member since 2010
James Goldenring, MD, PhD
Faculty Member
Member since 2010
Guoqiang Gu, Ph.D.
Faculty Investigator
Member since 2009
Antonis Hatzopoulos, Ph.D.
Faculty Member
Member since 2009
Scott Hiebert, Ph.D.
Faculty Member
Member since 2009
Charles Hong, M.D., Ph.D.
Faculty Member
Member since 2009
Rebecca Ihrie, Ph.D.
Faculty Member
Member since 2012
Mark Magnuson, M.D.
Director
Member since 2004
Susan Majka, PhD
Faculty Member
Member since 2012
Robert Matusik, Ph.D.
Faculty Member
Member since 2009
Douglas Mortlock, Ph.D.
Faculty Member
Member since 2009
Michelle Southard-Smith, Ph.D.
Faculty Member
Member since 2010
Hak-Joon Sung, Ph.D.
Faculty Member
Member since 2010
Chris Wright, D. Phil.
Faculty Investigator
Member since 2009
Pampee Young, MD, PhD
Faculty Member
Member since 2010
Sandra Zinkel, M.D., Ph.D.
Faculty Member
Member since 2009

News

Core Facility

Upcoming Meetings

There are no upcoming meetings. You can view past meetings instead.

General Information

Featured Publications

  1. Type 2 Diabetes and Congenital Hyperinsulinism Cause DNA Double-Strand Breaks and p53 Activity in β Cells. Tornovsky-Babeay S, Dadon D, Ziv O, Tzipilevich E, Kadosh T, Schyr-Ben Haroush R, Hija A, Stolovich-Rain M, Furth-Lavi J, Granot Z, Porat S, Philipson LH, Herold KC, Bhatti TR, Stanley C, Ashcroft FM, In't Veld P, Saada A, Magnuson MA, Glaser B, Dor Y (2014) Cell Metab 19(1): 109-21
    › Primary publication · 24332968 (PubMed)
  2. Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice. Baeyens L, Lemper M, Leuckx G, De Groef S, Bonfanti P, Stangé G, Shemer R, Nord C, Scheel DW, Pan FC, Ahlgren U, Gu G, Stoffers DA, Dor Y, Ferrer J, Gradwohl G, Wright CV, Van de Casteele M, German MS, Bouwens L, Heimberg H (2014) Nat Biotechnol 32(1): 76-83
    › Primary publication · 24240391 (PubMed)
  3. Malignant transformation of colonic epithelial cells by a colon-derived long noncoding RNA. Franklin JL, Rankin CR, Levy S, Snoddy JR, Zhang B, Washington MK, Thomson JM, Whitehead RH, Coffey RJ (2013) Biochem Biophys Res Commun 440(1): 99-104
    › Primary publication · 24045012 (PubMed) · PMC3875348 (PubMed Central)
  4. Identification and manipulation of biliary metaplasia in pancreatic tumors. Delgiorno KE, Hall JC, Takeuchi KK, Pan FC, Halbrook CJ, Washington MK, Olive KP, R Spence J, Sipos B, Wright CV, Wells JM, Crawford HC (2014) Gastroenterology 146(1): 233-244.e5
    › Primary publication · 23999170 (PubMed) · PMC3870045 (PubMed Central)
  5. Pancreas-specific cre driver lines and considerations for their prudent use. Magnuson MA, Osipovich AB (2013) Cell Metab 18(1): 9-20
    › Primary publication · 23823474 (PubMed)
  6. Synthesis and structure-activity relationships of a novel and selective bone morphogenetic protein receptor (BMP) inhibitor derived from the pyrazolo[1.5-a]pyrimidine scaffold of dorsomorphin: the discovery of ML347 as an ALK2 versus ALK3 selective MLPCN probe. Engers DW, Frist AY, Lindsley CW, Hong CC, Hopkins CR (2013) Bioorg Med Chem Lett 23(11): 3248-52
    › Primary publication · 23639540 (PubMed) · PMC3677712 (PubMed Central)
  7. Patient heal thyself: modeling and treating neurological disorders using patient-derived stem cells. Ess KC (2013) Exp Biol Med (Maywood) 238(3): 308-14
    › Primary publication · 23598977 (PubMed)
  8. Spatiotemporal patterns of multipotentiality in Ptf1a-expressing cells during pancreas organogenesis and injury-induced facultative restoration. Pan FC, Bankaitis ED, Boyer D, Xu X, Van de Casteele M, Magnuson MA, Heimberg H, Wright CV (2013) Development 140(4): 751-64
    › Primary publication · 23325761 (PubMed) · PMC3557774 (PubMed Central)
  9. Quantification of factors influencing fluorescent protein expression using RMCE to generate an allelic series in the ROSA26 locus in mice. Chen SX, Osipovich AB, Ustione A, Potter LA, Hipkens S, Gangula R, Yuan W, Piston DW, Magnuson MA (2011) Dis Model Mech 4(4): 537-47
    › Primary publication · 21324933 (PubMed) · PMC3124063 (PubMed Central)

©2004-2014 · Vanderbilt Center for Stem Cell Biology, Vanderbilt University Medical Center
Last modified on January 31, 2013. Technology and content provided by labnodes.vanderbilt.edu.