Events -- Beta Cell Interest Group (BIG)

The Role of MafA Gene in Adult Mouse Beta Cell Function

Tsunehiko Yamamoto
Postdoctoral Fellow
Stein Lab

Our pancreas-specific MafA null mice exhibited glucose intolerance by IPGTT during postnatal period, whereas there is no histological changing between KO and WT mice until 7 days, indicating that a phenotype closely is reminiscent of beta cell dysfunction found in human type 2 diabetes. We predict that MafA has been involved in beta cell function in postnatal period.

About this ongoing activity:

The Vanderbilt Center for Stem Cell Biology (VCSCB) sponsors a weekly Beta Cell Interest Group (BIG) meeting for invited Vanderbilt faculty, research assistants and students to discuss topics relating to beta cell biology. BIG meetings are held on Wednesdays from 9:00-10:00 AM in 512 Light Hall.