Nathan Mundell

Graduate Student

Phone: 615-322-4378
Fax: 615-343-2173
Email: nathan.mundell@vanderbilt.edu

Nathan is a graduate student in the Labosky lab and joined the department of Pharmacology after beginning the Interdisciplinary Graduate Program in Biomedical Sciences in 2004. Previously Nathan graduated from Western Kentucky University with a BS in Biology in 2002 and then worked on the role of transforming growth factor beta in heart development as a Research Assistant at Vanderbilt with Dr. Joey Barnett. His project in the Labosky lab focuses on understanding the molecular regulation of self-renewal and multipotency of neural crest stem cells. More specifically, he is using a Wnt1Cre transgenic allele to drive neural crest-specific deletion of the transcription factor Foxd3 in mice. By in vitro culture of neural crest progenitors from Foxd3 mutant embryos, it is possible to dissect the requirement of this gene for maintenance of multipotent neural crest subpopulations. He is currently funded by a predoctoral Ruth L. Kirschstein NRSA fellowship from the National Institutes of Neurological Disorders and Stroke.

Publications

PubMedID	Citation
18367558	Teng L, Mundell NA, Frist AY, Wang Q, Labosky PA. Requirement for Foxd3 in the maintenance of neural crest progenitors. (2008) Development 135: 1615-24
16258965	Compton LA, Potash DA, Mundell NA, Barnett JV. Transforming growth factor-beta induces loss of epithelial character and smooth muscle cell differentiation in epicardial cells. (2006) Dev Dyn 235: 82-93
16245329	Olivey HE, Mundell NA, Austin AF, Barnett JV. Transforming growth factor-beta stimulates epithelial-mesenchymal transformation in the proepicardium. (2006) Dev Dyn 235: 50-9
15766759	Desgrosellier JS, Mundell NA, McDonnell MA, Moses HL, Barnett JV. Activin receptor-like kinase 2 and Smad6 regulate epithelial-mesenchymal transformation during cardiac valve formation. (2005) Dev Biol 280: 201-10