I began my career as a research assistant at Vanderbilt shortly after earning my B.S. in Biology from the University of Tennessee. My first position was in the Division of Endocrinology where I worked with Dr. David Rabin performing clinical research in human infertility and hormone production. I joined the Magnuson lab in 1991. I have been involved in many interesting projects including development of the Transgenic Mouse ES Cell/Shared Resource and numerous gene targeting projects that utilize mouse embryonic stem cells for the generation of genetically altered mice. My loves outside the lab include time with family, gardening, hiking and biking.
| PubMedID | Citation |
|---|---|
| 17353190 | Pino MF, Kim KA, Shelton KD, Lindner J, Odili S, Li C, Collins HW, Shiota M, Matschinsky FM, Magnuson MA. Glucokinase thermolability and hepatic regulatory protein binding are essential factors for predicting the blood glucose phenotype of missense mutations. (2007) J Biol Chem 282: 13906-16 |
| 16962829 | Shiota C, Woo JT, Lindner J, Shelton KD, Magnuson MA. Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability. (2006) Dev Cell 11: 583-9 |
| 15833818 | Jones JR, Barrick C, Kim KA, Lindner J, Blondeau B, Fujimoto Y, Shiota M, Kesterson RA, Kahn BB, Magnuson MA. Deletion of PPARgamma in adipose tissues of mice protects against high fat diet-induced obesity and insulin resistance. (2005) Proc Natl Acad Sci U S A 102: 6207-12 |
| 15286998 | Long Q, Shelton KD, Lindner J, Jones JR, Magnuson MA. Efficient DNA cassette exchange in mouse embryonic stem cells by staggered positive-negative selection. (2004) Genesis 39: 256-62 |
| 12149271 | Shiota C, Larsson O, Shelton KD, Shiota M, Efanov AM, Hoy M, Lindner J, Kooptiwut S, Juntti-Berggren L, Gromada J, Berggren PO, Magnuson MA. Sulfonylurea receptor type 1 knock-out mice have intact feeding-stimulated insulin secretion despite marked impairment in their response to glucose. (2002) J Biol Chem 277: 37176-83 |
| 9867845 | Postic C, Shiota M, Niswender KD, Jetton TL, Chen Y, Moates JM, Shelton KD, Lindner J, Cherrington AD, Magnuson MA. Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase. (1999) J Biol Chem 274: 305-15 |
| 9671733 | Jetton TL, Moates JM, Lindner J, Wright CV, Magnuson MA. Targeted oncogenesis of hormone-negative pancreatic islet progenitor cells. (1998) Proc Natl Acad Sci U S A 95: 8654-9 |
| 8843087 | Wang R, Macmillan LB, Fremeau RT, Magnuson MA, Lindner J, Limbird LE. Expression of alpha 2-adrenergic receptor subtypes in the mouse brain: evaluation of spatial and temporal information imparted by 3 kb of 5' regulatory sequence for the alpha 2A AR-receptor gene in transgenic animals. (1996) Neuroscience 74: 199-218 |
| 7007403 | Lindner J, McNeil LW, Marney S, Conway M, Rivier J, Vale W, Rabin D. Characterization of human anti-luteinizing hormone-releasing hormone (LRH) antibodies in the serum of a patient with isolated gonadotropin deficiency treated with synthetic LRH. (1981) J Clin Endocrinol Metab 52: 267-70 |
| 6802737 | Linde R, Lindner J, Lorber D, Rabin D. Dissociation of LH and FSH Responses to LHRH during estrogen therapy of patients with ovarian failure. (1982) Horm Metab Res 14: 154-6 |
| 6228566 | Evans RM, Doelle GC, Lindner J, Bradley V, Rabin D. A luteinizing hormone-releasing hormone agonist decreases biological activity and modifies chromatographic behavior of luteinizing hormone in man. (1984) J Clin Invest 73: 262-6 |
| 2834409 | Pavlou SN, Dahl KD, Wakefield G, Rivier J, Vale W, Hsueh AJ, Lindner J. Maintenance of the ratio of bioactive to immunoreactive follicle-stimulating hormone in normal men during chronic luteinizing hormone-releasing hormone agonist administration. (1988) J Clin Endocrinol Metab 66: 1005-9 |
| 2537334 | Pavlou SN, Wakefield G, Schlechter NL, Lindner J, Souza KH, Kamilaris TC, Konidaris S, Rivier JE, Vale WW, Toglia M. Mode of suppression of pituitary and gonadal function after acute or prolonged administration of a luteinizing hormone-releasing hormone antagonist in normal men. (1989) J Clin Endocrinol Metab 68: 446-54 |
| 2110578 | Pavlou SN, Veldhuis JD, Lindner J, Souza KH, Urban RJ, Rivier JE, Vale WW, Stallard DJ. Persistence of concordant luteinizing hormone (LH), testosterone, and alpha-subunit pulses after LH-releasing hormone antagonist administration in normal men. (1990) J Clin Endocrinol Metab 70: 1472-8 |
| 1955518 | Pavlou SN, Brewer K, Farley MG, Lindner J, Bastias MC, Rogers BJ, Swift LL, Rivier JE, Vale WW, Conn PM. Combined administration of a gonadotropin-releasing hormone antagonist and testosterone in men induces reversible azoospermia without loss of libido. (1991) J Clin Endocrinol Metab 73: 1360-9 |
| 1690747 | Lindner J, Rivier JE, Vale WW, Pavlou SN. Regulation of pituitary glycoprotein alpha-subunit secretion after administration of a luteinizing hormone-releasing hormone antagonist in normal men. (1990) J Clin Endocrinol Metab 70: 1219-24 |
| 572760 | Benveniste R, Lindner J, Puett D, Rabin D. Human chorionic gonadotropin alpha-subunit from cultured choriocarcinoma (JEG) cells: comparison of the subunit secreted free with that prepared from secreted human chorionic gonadotropin. (1979) Endocrinology 105: 581-7 |
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