Our Mission

Mission Statement

The Vanderbilt Center for Stem Cell Biology (VCSCB) is a participation-based entity that brings together investigators interested in stem and/or progenitor cell biology. By stimulating scientific interactions, we strive to broadly propel and elevate the generation of new knowledge related to tissue and organ development with strong emphasis on the cellular and genetic mechanisms that regulate cell fate specification, plasticity and maintenance.

Goals and Activities

Our goal is to advance individual and team-based research activities that relate to stem and progenitor-cell biology. To do so, we place a high priority on graduate and post-doctoral training, the exchange of state-of-the-art knowledge, and the oversight of two shared resources that provide access to critical technology. To enhance graduate and post-doctoral training, we co-operate with the trans-institutional Vanderbilt Program in Developmental Biology, led by Dr. Chris Wright. To exchange state-of-the-art knowledge, we organize and host the bi-weekly SPRING seminar series, and periodically bring in external speakers, either in co-operation with the departmental Cell & Developmental Biology seminar series, or by organizing day-long VCSCB Symposia with internationally renowned speakers. To provide easy access to key technological tools and strategies, both the Vanderbilt Genome-Editing Resource (VGER) and Creative Data Solutions (CDS) reside within this Center.

Core Principle

We are dedicated to training the next generation of scientists. This requires that we place a high priority on discovery science, creative scholarship, effective communication, and high-impact publication.


Mark Magnuson, M.D., Director
Chris Wright, D. Phil., Associate Director

Executive Committee

Ed Levine, Ph.D.
Ethan Lippmann, Ph.D.
Mark Magnuson, M.D.
Michelle Southard-Smith, Ph.D.
Chris Wright, D. Phil.

Contact Us
A listing of upcoming events or seminars that you might want to attend.
When and where Topic and related details
View more meetings
Oct. 5
9:00 AM
SPRING Meeting
Amanda Ruelas, Amelia Cephas (grad students)
Oct. 19
9:00 AM
SPRING Meeting
Jonathan Irish, Ph.D.
Nov. 2
9:00 AM
SPRING Meeting
Jeff Rathmell, Ph.D. and Leesa Sampson, Ph.D.
Latest Publications
  1. Microtubules regulate pancreatic β-cell heterogeneity via spatiotemporal control of insulin secretion hot spots. Trogden KP, Lee J, Bracey KM, Ho KH, McKinney H, Zhu X, Arpag G, Folland TG, Osipovich AB, Magnuson MA, Zanic M, Gu G, Holmes WR, Kaverina I (2021) Elife
    › Primary publication · 34783306 (PubMed) · PMC8635970 (PubMed Central)
  2. Insm1, Neurod1, and Pax6 promote murine pancreatic endocrine cell development through overlapping yet distinct RNA transcription and splicing programs. Dudek KD, Osipovich AB, Cartailler JP, Gu G, Magnuson MA (2021) G3 (Bethesda) 11(11)
    › Primary publication · 34534285 (PubMed) · PMC8527475 (PubMed Central)
  3. Temporal Transcriptome Analysis Reveals Dynamic Gene Expression Patterns Driving β-Cell Maturation. Sanavia T, Huang C, Manduchi E, Xu Y, Dadi PK, Potter LA, Jacobson DA, Di Camillo B, Magnuson MA, Stoeckert CJ, Gu G (2021) Front Cell Dev Biol : 648791
    › Primary publication · 34017831 (PubMed) · PMC8129579 (PubMed Central)
  4. A developmental lineage-based gene co-expression network for mouse pancreatic β-cells reveals a role for in pancreas development. Osipovich AB, Dudek KD, Greenfest-Allen E, Cartailler JP, Manduchi E, Potter Case L, Choi E, Chapman AG, Clayton HW, Gu G, Stoeckert CJ, Magnuson MA (2021) Development 148(6)
    › Primary publication · 33653874 (PubMed) · PMC8015253 (PubMed Central)
  5. Glucose Regulates Microtubule Disassembly and the Dose of Insulin Secretion via Tau Phosphorylation. Ho KH, Yang X, Osipovich AB, Cabrera O, Hayashi ML, Magnuson MA, Gu G, Kaverina I (2020) Diabetes 69(9): 1936-1947
    › Primary publication · 32540877 (PubMed) · PMC7458041 (PubMed Central)
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