Microtubules regulate pancreatic β-cell heterogeneity via spatiotemporal control of insulin secretion hot spots. Trogden KP, Lee J, Bracey KM, Ho KH, McKinney H, Zhu X, Arpag G, Folland TG, Osipovich AB, Magnuson MA, Zanic M, Gu G, Holmes WR, Kaverina I (2021) Elife › Primary publication · 34783306 (PubMed) · PMC8635970 (PubMed Central)
Insm1, Neurod1, and Pax6 promote murine pancreatic endocrine cell development through overlapping yet distinct RNA transcription and splicing programs. Dudek KD, Osipovich AB, Cartailler JP, Gu G, Magnuson MA (2021) G3 (Bethesda)11(11) › Primary publication · 34534285 (PubMed) · PMC8527475 (PubMed Central)
Temporal Transcriptome Analysis Reveals Dynamic Gene Expression Patterns Driving β-Cell Maturation. Sanavia T, Huang C, Manduchi E, Xu Y, Dadi PK, Potter LA, Jacobson DA, Di Camillo B, Magnuson MA, Stoeckert CJ, Gu G (2021) Front Cell Dev Biol : 648791 › Primary publication · 34017831 (PubMed) · PMC8129579 (PubMed Central)
A developmental lineage-based gene co-expression network for mouse pancreatic β-cells reveals a role for in pancreas development. Osipovich AB, Dudek KD, Greenfest-Allen E, Cartailler JP, Manduchi E, Potter Case L, Choi E, Chapman AG, Clayton HW, Gu G, Stoeckert CJ, Magnuson MA (2021) Development148(6) › Primary publication · 33653874 (PubMed) · PMC8015253 (PubMed Central)
Glucose Regulates Microtubule Disassembly and the Dose of Insulin Secretion via Tau Phosphorylation. Ho KH, Yang X, Osipovich AB, Cabrera O, Hayashi ML, Magnuson MA, Gu G, Kaverina I (2020) Diabetes69(9): 1936-1947 › Primary publication · 32540877 (PubMed) · PMC7458041 (PubMed Central)
Myt Transcription Factors Prevent Stress-Response Gene Overactivation to Enable Postnatal Pancreatic β Cell Proliferation, Function, and Survival. Hu R, Walker E, Huang C, Xu Y, Weng C, Erickson GE, Coldren A, Yang X, Brissova M, Kaverina I, Balamurugan AN, Wright CVE, Li Y, Stein R, Gu G (2020) Dev Cell53(4): 390-405.e10 › Primary publication · 32359405 (PubMed) · PMC7278035 (PubMed Central)
Excitotoxicity and Overnutrition Additively Impair Metabolic Function and Identity of Pancreatic β-Cells. Osipovich AB, Stancill JS, Cartailler JP, Dudek KD, Magnuson MA (2020) Diabetes69(7): 1476-1491 › Primary publication · 32332159 (PubMed) · PMC7809715 (PubMed Central)
Coregulator Sin3a Promotes Postnatal Murine β-Cell Fitness by Regulating Genes in Ca Homeostasis, Cell Survival, Vesicle Biosynthesis, Glucose Metabolism, and Stress Response. Yang X, Graff SM, Heiser CN, Ho KH, Chen B, Simmons AJ, Southard-Smith AN, David G, Jacobson DA, Kaverina I, Wright CVE, Lau KS, Gu G (2020) Diabetes69(6): 1219-1231 › Primary publication · 32245798 (PubMed) · PMC7243292 (PubMed Central)
Gene network transitions in embryos depend upon interactions between a pioneer transcription factor and core histones. Iwafuchi M, Cuesta I, Donahue G, Takenaka N, Osipovich AB, Magnuson MA, Roder H, Seeholzer SH, Santisteban P, Zaret KS (2020) Nat Genet52(4): 418-427 › Primary publication · 32203463 (PubMed) · PMC7901023 (PubMed Central)
Retraction Note: Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice. Baeyens L, Lemper M, Leuckx G, De Groef S, Bonfanti P, Stangé G, Shemer R, Nord C, Scheel DW, Pan FC, Ahlgren U, Gu G, Stoffers DA, Dor Y, Ferrer J, Gradwohl G, Wright CVE, Van de Casteele M, German MS, Bouwens L, Heimberg H (2020) Nat Biotechnol38(3): 374 › Primary publication · 32066957 (PubMed) · PMC7175803 (PubMed Central)
Inactivation of mTORC2 in macrophages is a signature of colorectal cancer that promotes tumorigenesis. Katholnig K, Schütz B, Fritsch SD, Schörghofer D, Linke M, Sukhbaatar N, Matschinger JM, Unterleuthner D, Hirtl M, Lang M, Herac M, Spittler A, Bergthaler A, Schabbauer G, Bergmann M, Dolznig H, Hengstschläger M, Magnuson MA, Mikula M, Weichhart T (2019) JCI Insight4(20) › Primary publication · 31619583 (PubMed) · PMC6824305 (PubMed Central)
The BRG1/SOX9 axis is critical for acinar cell-derived pancreatic tumorigenesis. Tsuda M, Fukuda A, Roy N, Hiramatsu Y, Leonhardt L, Kakiuchi N, Hoyer K, Ogawa S, Goto N, Ikuta K, Kimura Y, Matsumoto Y, Takada Y, Yoshioka T, Maruno T, Yamaga Y, Kim GE, Akiyama H, Ogawa S, Wright CV, Saur D, Takaori K, Uemoto S, Hebrok M, Chiba T, Seno H (2018) J Clin Invest128(8): 3475-3489 › Primary publication · 30010625 (PubMed) · PMC6063489 (PubMed Central)
Forebrain Ptf1a Is Required for Sexual Differentiation of the Brain. Fujiyama T, Miyashita S, Tsuneoka Y, Kanemaru K, Kakizaki M, Kanno S, Ishikawa Y, Yamashita M, Owa T, Nagaoka M, Kawaguchi Y, Yanagawa Y, Magnuson MA, Muratani M, Shibuya A, Nabeshima YI, Yanagisawa M, Funato H, Hoshino M (2018) Cell Rep24(1): 79-94 › Primary publication · 29972793 (PubMed)
Genome Editing and Induced Pluripotent Stem Cell Technologies for Personalized Study of Cardiovascular Diseases. Chun YW, Durbin MD, Hong CC (2018) Curr Cardiol Rep20(6): 38 › Primary publication · 29666931 (PubMed) · PMC6204334 (PubMed Central)
Synaptotagmin 4 Regulates Pancreatic β Cell Maturation by Modulating the Ca Sensitivity of Insulin Secretion Vesicles. Huang C, Walker EM, Dadi PK, Hu R, Xu Y, Zhang W, Sanavia T, Mun J, Liu J, Nair GG, Tan HYA, Wang S, Magnuson MA, Stoeckert CJ, Hebrok M, Gannon M, Han W, Stein R, Jacobson DA, Gu G (2018) Dev Cell45(3): 347-361.e5 › Primary publication · 29656931 (PubMed) · PMC5962294 (PubMed Central)
Cytosolic phosphoenolpyruvate carboxykinase as a cataplerotic pathway in the small intestine. Potts A, Uchida A, Deja S, Berglund ED, Kucejova B, Duarte JA, Fu X, Browning JD, Magnuson MA, Burgess SC (2018) Am J Physiol Gastrointest Liver Physiol315(2): G249-G258 › Primary publication · 29631378 (PubMed) · PMC6139646 (PubMed Central)
Formation of retinal direction-selective circuitry initiated by starburst amacrine cell homotypic contact. Ray TA, Roy S, Kozlowski C, Wang J, Cafaro J, Hulbert SW, Wright CV, Field GD, Kay JN (2018) Elife › Primary publication · 29611808 (PubMed) · PMC5931800 (PubMed Central)
ARID1A Maintains Differentiation of Pancreatic Ductal Cells and Inhibits Development of Pancreatic Ductal Adenocarcinoma in Mice. Kimura Y, Fukuda A, Ogawa S, Maruno T, Takada Y, Tsuda M, Hiramatsu Y, Araki O, Nagao M, Yoshikawa T, Ikuta K, Yoshioka T, Wang Z, Akiyama H, Wright CV, Takaori K, Uemoto S, Chiba T, Seno H (2018) Gastroenterology155(1): 194-209.e2 › Primary publication · 29604291 (PubMed)
An immunogenic cell injury module for the single-cell multiplexed activity metabolomics platform to identify promising anti-cancer natural products. Balsamo JA, Penton KE, Zhao Z, Hayes MJ, Lima SM, Irish JM, Bachmann BO (2022) J Biol Chem298(9): 102300 › Primary publication · 35931117 (PubMed) · PMC9424577 (PubMed Central)
Systems Immunology Analyses of Gain-of-Function Immune Phenotypes Reveal Heterogeneous Response to IL-6 and Broad Immunometabolic Roles for STAT1. Kaviany S, Bartkowiak T, Dulek DE, Khan YW, Hayes MJ, Schaefer SG, Ye X, Dahunsi DO, Connelly JA, Irish JM, Rathmell JC (2022) Immunohorizons6(7): 447-464 › Primary publication · 35840326 (PubMed) · PMC9623573 (PubMed Central)
The Casein kinase 1α agonist pyrvinium attenuates Wnt-mediated CK1α degradation via interaction with the E3 ubiquitin ligase component Cereblon. Shen C, Nayak A, Neitzel LR, Yang F, Li B, Williams CH, Hong CC, Ahmed Y, Lee E, Robbins DJ (2022) J Biol Chem298(8): 102227 › Primary publication · 35780831 (PubMed) · PMC9352546 (PubMed Central)
Single-cell profiling of the antigen-specific response to BNT162b2 SARS-CoV-2 RNA vaccine. Kramer KJ, Wilfong EM, Voss K, Barone SM, Shiakolas AR, Raju N, Roe CE, Suryadevara N, Walker LM, Wall SC, Paulo A, Schaefer S, Dahunsi D, Westlake CS, Crowe JE, Carnahan RH, Rathmell JC, Bonami RH, Georgiev IS, Irish JM (2022) Nat Commun13(1): 3466 › Primary publication · 35710908 (PubMed) · PMC9201272 (PubMed Central)
Utilizing Three-Dimensional Culture Methods to Improve High-Throughput Drug Screening in Anaplastic Thyroid Carcinoma. Bergdorf K, Bauer JA, Westover D, Phifer C, Murphy B, Tyson DR, Lee E, Weiss VL (2022) Cancers (Basel)14(8) › Primary publication · 35454763 (PubMed) · PMC9031362 (PubMed Central)
Nonclassical Monocytes Are Prone to Migrate Into Tumor in Diffuse Large B-Cell Lymphoma. Le Gallou S, Lhomme F, Irish JM, Mingam A, Pangault C, Monvoisin C, Ferrant J, Azzaoui I, Rossille D, Bouabdallah K, Damaj G, Cartron G, Godmer P, Le Gouill S, Casasnovas RO, Molina TJ, Houot R, Lamy T, Tarte K, Fest T, Roussel M (2021) Front Immunol : 755623 › Primary publication · 34975843 (PubMed) · PMC8716558 (PubMed Central)
DDR1 contributes to kidney inflammation and fibrosis by promoting the phosphorylation of BCR and STAT3. Borza CM, Bolas G, Bock F, Zhang X, Akabogu FC, Zhang MZ, de Caestecker M, Yang M, Yang H, Lee E, Gewin L, Fogo AB, McDonald WH, Zent R, Pozzi A (2022) JCI Insight7(3) › Primary publication · 34941574 (PubMed) · PMC8855801 (PubMed Central)
Two New Neutrophil Subsets Define a Discriminating Sepsis Signature. Meghraoui-Kheddar A, Chousterman BG, Guillou N, Barone SM, Granjeaud S, Vallet H, Corneau A, Guessous K, de Roquetaillade C, Boissonnas A, Irish JM, Combadière C (2022) Am J Respir Crit Care Med205(1): 46-59 › Primary publication · 34731593 (PubMed)
Insm1, Neurod1, and Pax6 promote murine pancreatic endocrine cell development through overlapping yet distinct RNA transcription and splicing programs. Dudek KD, Osipovich AB, Cartailler JP, Gu G, Magnuson MA (2021) G3 (Bethesda)11(11) › Primary publication · 34534285 (PubMed) · PMC8527475 (PubMed Central)
The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling. Shen C, Nayak A, Neitzel LR, Adams AA, Silver-Isenstadt M, Sawyer LM, Benchabane H, Wang H, Bunnag N, Li B, Wynn DT, Yang F, Garcia-Contreras M, Williams CH, Dakshanamurthy S, Hong CC, Ayad NG, Capobianco AJ, Ahmed Y, Lee E, Robbins DJ (2021) Nat Commun12(1): 5263 › Primary publication · 34489457 (PubMed) · PMC8421366 (PubMed Central)
Unsupervised machine learning reveals key immune cell subsets in COVID-19, rhinovirus infection, and cancer therapy. Barone SM, Paul AG, Muehling LM, Lannigan JA, Kwok WW, Turner RB, Woodfolk JA, Irish JM (2021) Elife › Primary publication · 34350827 (PubMed) · PMC8370768 (PubMed Central)
Single-Cell Profiling of the Antigen-Specific Response to BNT162b2 SARS-CoV-2 RNA Vaccine. Kramer KJ, Wilfong EM, Voss K, Barone SM, Shiakolas AR, Raju N, Roe CE, Suryadevara N, Walker L, Wall SC, Paulo A, Schaefer S, Dahunsi D, Westlake CS, Crowe JE, Carnahan RH, Rathmell JC, Bonami RH, Georgiev IS, Irish JM (2021) bioRxiv › Primary publication · 34341788 (PubMed) · PMC8328055 (PubMed Central)
Selective Inhibition of JAK1 Primes STAT5-Driven Human Leukemia Cells for ATRA-Induced Differentiation. Ramsey HE, Stengel K, Pino JC, Johnston G, Childress M, Gorska AE, Arrate PM, Fuller L, Villaume M, Fischer MA, Ferrell PB, Roe CE, Zou J, Lubbock ALR, Stubbs M, Zinkel S, Irish JM, Lopez CF, Hiebert S, Savona MR (2021) Target Oncol16(5): 663-674 › Primary publication · 34324169 (PubMed) · PMC8667588 (PubMed Central)
HLA-DR cancer cells expression correlates with T cell infiltration and is enriched in lung adenocarcinoma with indolent behavior. Senosain MF, Zou Y, Novitskaya T, Vasiukov G, Balar AB, Rowe DJ, Doxie DB, Lehman JM, Eisenberg R, Maldonado F, Zijlstra A, Novitskiy SV, Irish JM, Massion PP (2021) Sci Rep11(1): 14424 › Primary publication · 34257356 (PubMed) · PMC8277797 (PubMed Central)
Immunofluorescent staining of cancer spheroids and fine-needle aspiration-derived organoids. Bergdorf KN, Phifer CJ, Bechard ME, Lee MA, McDonald OG, Lee E, Weiss VL (2021) STAR Protoc2(2): 100578 › Primary publication · 34136836 (PubMed) · PMC8182106 (PubMed Central)
CMV exposure drives long-term CD57+ CD4 memory T-cell inflation following allogeneic stem cell transplant. Yeh AC, Varelias A, Reddy A, Barone SM, Olver SD, Chilson K, Onstad LE, Ensbey KS, Henden AS, Samson L, Jaeger CA, Bi T, Dahlman KB, Kim TK, Zhang P, Degli-Esposti MA, Newell EW, Jagasia MH, Irish JM, Lee SJ, Hill GR (2021) Blood138(26): 2874-2885 › Primary publication · 34115118 (PubMed) · PMC8718626 (PubMed Central)
Temporal Transcriptome Analysis Reveals Dynamic Gene Expression Patterns Driving β-Cell Maturation. Sanavia T, Huang C, Manduchi E, Xu Y, Dadi PK, Potter LA, Jacobson DA, Di Camillo B, Magnuson MA, Stoeckert CJ, Gu G (2021) Front Cell Dev Biol : 648791 › Primary publication · 34017831 (PubMed) · PMC8129579 (PubMed Central)
Single-cell analysis by mass cytometry reveals metabolic states of early-activated CD8 T cells during the primary immune response. Levine LS, Hiam-Galvez KJ, Marquez DM, Tenvooren I, Madden MZ, Contreras DC, Dahunsi DO, Irish JM, Oluwole OO, Rathmell JC, Spitzer MH (2021) Immunity54(4): 829-844.e5 › Primary publication · 33705706 (PubMed) · PMC8046726 (PubMed Central)
A developmental lineage-based gene co-expression network for mouse pancreatic β-cells reveals a role for in pancreas development. Osipovich AB, Dudek KD, Greenfest-Allen E, Cartailler JP, Manduchi E, Potter Case L, Choi E, Chapman AG, Clayton HW, Gu G, Stoeckert CJ, Magnuson MA (2021) Development148(6) › Primary publication · 33653874 (PubMed) · PMC8015253 (PubMed Central)
Circulating Myeloid Regulatory Cells: Promising Biomarkers in B-Cell Lymphomas. Ferrant J, Lhomme F, Le Gallou S, Irish JM, Roussel M (2020) Front Immunol : 623993 › Primary publication · 33603754 (PubMed) · PMC7884747 (PubMed Central)
Induction of Wnt signaling antagonists and p21-activated kinase enhances cardiomyocyte proliferation during zebrafish heart regeneration. Peng X, Lai KS, She P, Kang J, Wang T, Li G, Zhou Y, Sun J, Jin D, Xu X, Liao L, Liu J, Lee E, Poss KD, Zhong TP (2021) J Mol Cell Biol13(1): 41-58 › Primary publication · 33582796 (PubMed) · PMC8035995 (PubMed Central)
Targeting In Vivo Metabolic Vulnerabilities of Th2 and Th17 Cells Reduces Airway Inflammation. Healey DCC, Cephus JY, Barone SM, Chowdhury NU, Dahunsi DO, Madden MZ, Ye X, Yu X, Olszewski K, Young K, Gerriets VA, Siska PJ, Dworski R, Hemler J, Locasale JW, Poyurovsky MV, Peebles RS, Irish JM, Newcomb DC, Rathmell JC (2021) J Immunol206(6): 1127-1139 › Primary publication · 33558372 (PubMed) · PMC7946768 (PubMed Central)
Obtaining patient-derived cancer organoid cultures via fine-needle aspiration. Phifer CJ, Bergdorf KN, Bechard ME, Vilgelm A, Baregamian N, McDonald OG, Lee E, Weiss VL (2021) STAR Protoc2(1): 100220 › Primary publication · 33377121 (PubMed) · PMC7758553 (PubMed Central)
High-throughput drug screening of fine-needle aspiration-derived cancer organoids. Bergdorf K, Phifer C, Bharti V, Westover D, Bauer J, Vilgelm A, Lee E, Weiss V (2020) STAR Protoc1(3): 100212 › Primary publication · 33377106 (PubMed) · PMC7757655 (PubMed Central)
A Cytometrist's Guide to Coordinating and Performing Effective COVID-19 Research. Chattopadhyay PK, Filby A, Jellison ER, Ferrari G, Green C, Cherian S, Irish J, Litwin V, other members of the ISAC COVID-19 Work Group (2021) Cytometry A99(1): 11-18 › Primary publication · 32881296 (PubMed) · PMC7461086 (PubMed Central)
Casein Kinase 1α as a Regulator of Wnt-Driven Cancer. Shen C, Nayak A, Melendez RA, Wynn DT, Jackson J, Lee E, Ahmed Y, Robbins DJ (2020) Int J Mol Sci21(16) › Primary publication · 32824859 (PubMed) · PMC7460588 (PubMed Central)
CD28 costimulation drives tumor-infiltrating T cell glycolysis to promote inflammation. Beckermann KE, Hongo R, Ye X, Young K, Carbonell K, Healey DCC, Siska PJ, Barone S, Roe CE, Smith CC, Vincent BG, Mason FM, Irish JM, Rathmell WK, Rathmell JC (2020) JCI Insight5(16) › Primary publication · 32814710 (PubMed) · PMC7455120 (PubMed Central)
Fine-Needle Aspiration-Based Patient-Derived Cancer Organoids. Vilgelm AE, Bergdorf K, Wolf M, Bharti V, Shattuck-Brandt R, Blevins A, Jones C, Phifer C, Lee M, Lowe C, Hongo R, Boyd K, Netterville J, Rohde S, Idrees K, Bauer JA, Westover D, Reinfeld B, Baregamian N, Richmond A, Rathmell WK, Lee E, McDonald OG, Weiss VL (2020) iScience23(8): 101408 › Primary publication · 32771978 (PubMed) · PMC7415927 (PubMed Central)
Unsupervised machine learning reveals key immune cell subsets in COVID-19, rhinovirus infection, and cancer therapy. Barone SM, Paul AGA, Muehling LM, Lannigan JA, Kwok WW, Turner RB, Woodfolk JA, Irish JM (2020) bioRxiv › Primary publication · 32766581 (PubMed) · PMC7402038 (PubMed Central)
Nuclear Regulation of Wnt/β-Catenin Signaling: It's a Complex Situation. Anthony CC, Robbins DJ, Ahmed Y, Lee E (2020) Genes (Basel)11(8) › Primary publication · 32759724 (PubMed) · PMC7465203 (PubMed Central)
Tuft Cells Inhibit Pancreatic Tumorigenesis in Mice by Producing Prostaglandin D. DelGiorno KE, Chung CY, Vavinskaya V, Maurer HC, Novak SW, Lytle NK, Ma Z, Giraddi RR, Wang D, Fang L, Naeem RF, Andrade LR, Ali WH, Tseng H, Tsui C, Gubbala VB, Ridinger-Saison M, Ohmoto M, Erikson GA, O'Connor C, Shokhirev MN, Hah N, Urade Y, Matsumoto I, Kaech SM, Singh PK, Manor U, Olive KP, Wahl GM (2020) Gastroenterology159(5): 1866-1881.e8 › Primary publication · 32717220 (PubMed) · PMC7680354 (PubMed Central)
Glucose Regulates Microtubule Disassembly and the Dose of Insulin Secretion via Tau Phosphorylation. Ho KH, Yang X, Osipovich AB, Cabrera O, Hayashi ML, Magnuson MA, Gu G, Kaverina I (2020) Diabetes69(9): 1936-1947 › Primary publication · 32540877 (PubMed) · PMC7458041 (PubMed Central)
Glucose Regulates Microtubule Disassembly and the Dose of Insulin Secretion via Tau Phosphorylation. Ho KH, Yang X, Osipovich AB, Cabrera O, Hayashi ML, Magnuson MA, Gu G, Kaverina I (2020) Diabetes69(9): 1936-1947 › Primary publication · 32540877 (PubMed) · PMC7458041 (PubMed Central)
Break on Through: Golgi-Derived Vesicles Aid in Mitochondrial Fission. Rasmussen ML, Robertson GL, Gama V (2020) Cell Metab31(6): 1047-1049 › Primary publication · 32492390 (PubMed) · PMC8212386 (PubMed Central)
A connection in life and death: The BCL-2 family coordinates mitochondrial network dynamics and stem cell fate. Rasmussen ML, Gama V (2020) Int Rev Cell Mol Biol : 255-284 › Primary publication · 32381177 (PubMed) · PMC7331972 (PubMed Central)
Tubular β-catenin and FoxO3 interactions protect in chronic kidney disease. Nlandu-Khodo S, Osaki Y, Scarfe L, Yang H, Phillips-Mignemi M, Tonello J, Saito-Diaz K, Neelisetty S, Ivanova A, Huffstater T, McMahon R, Taketo MM, deCaestecker M, Kasinath B, Harris RC, Lee E, Gewin LS (2020) JCI Insight5(10) › Primary publication · 32369448 (PubMed) · PMC7259539 (PubMed Central)
Myt Transcription Factors Prevent Stress-Response Gene Overactivation to Enable Postnatal Pancreatic β Cell Proliferation, Function, and Survival. Hu R, Walker E, Huang C, Xu Y, Weng C, Erickson GE, Coldren A, Yang X, Brissova M, Kaverina I, Balamurugan AN, Wright CVE, Li Y, Stein R, Gu G (2020) Dev Cell53(4): 390-405.e10 › Primary publication · 32359405 (PubMed) · PMC7278035 (PubMed Central)
Excitotoxicity and Overnutrition Additively Impair Metabolic Function and Identity of Pancreatic β-Cells. Osipovich AB, Stancill JS, Cartailler JP, Dudek KD, Magnuson MA (2020) Diabetes69(7): 1476-1491 › Primary publication · 32332159 (PubMed) · PMC7809715 (PubMed Central)
Treg sensitivity to FasL and relative IL-2 deprivation drive idiopathic aplastic anemia immune dysfunction. Lim SP, Costantini B, Mian SA, Perez Abellan P, Gandhi S, Martinez Llordella M, Lozano JJ, Antunes Dos Reis R, Povoleri GAM, Mourikis TP, Abarrategi A, Ariza-McNaughton L, Heck S, Irish JM, Lombardi G, Marsh JCW, Bonnet D, Kordasti S, Mufti GJ (2020) Blood136(7): 885-897 › Primary publication · 32294156 (PubMed) · PMC7532000 (PubMed Central)
High-Dimensional Data Analysis Algorithms Yield Comparable Results for Mass Cytometry and Spectral Flow Cytometry Data. Ferrer-Font L, Mayer JU, Old S, Hermans IF, Irish J, Price KM (2020) Cytometry A97(8): 824-831 › Primary publication · 32293794 (PubMed) · PMC7682594 (PubMed Central)
MCL-1 Inhibition by Selective BH3 Mimetics Disrupts Mitochondrial Dynamics Causing Loss of Viability and Functionality of Human Cardiomyocytes. Rasmussen ML, Taneja N, Neininger AC, Wang L, Robertson GL, Riffle SN, Shi L, Knollmann BC, Burnette DT, Gama V (2020) iScience23(4): 101015 › Primary publication · 32283523 (PubMed) · PMC7155208 (PubMed Central)
Precise Tuning of Cortical Contractility Regulates Cell Shape during Cytokinesis. Taneja N, Bersi MR, Baillargeon SM, Fenix AM, Cooper JA, Ohi R, Gama V, Merryman WD, Burnette DT (2020) Cell Rep31(1): 107477 › Primary publication · 32268086 (PubMed) · PMC8223100 (PubMed Central)
Training Novices in Generation and Analysis of High-Dimensional Human Cell Phospho-Flow Cytometry Data. Roe CE, Hayes MJ, Barone SM, Irish JM (2020) Curr Protoc Cytom93(1): e71 › Primary publication · 32250555 (PubMed) · PMC7682619 (PubMed Central)
Coregulator Sin3a Promotes Postnatal Murine β-Cell Fitness by Regulating Genes in Ca Homeostasis, Cell Survival, Vesicle Biosynthesis, Glucose Metabolism, and Stress Response. Yang X, Graff SM, Heiser CN, Ho KH, Chen B, Simmons AJ, Southard-Smith AN, David G, Jacobson DA, Kaverina I, Wright CVE, Lau KS, Gu G (2020) Diabetes69(6): 1219-1231 › Primary publication · 32245798 (PubMed) · PMC7243292 (PubMed Central)
Cysteine depletion induces pancreatic tumor ferroptosis in mice. Badgley MA, Kremer DM, Maurer HC, DelGiorno KE, Lee HJ, Purohit V, Sagalovskiy IR, Ma A, Kapilian J, Firl CEM, Decker AR, Sastra SA, Palermo CF, Andrade LR, Sajjakulnukit P, Zhang L, Tolstyka ZP, Hirschhorn T, Lamb C, Liu T, Gu W, Seeley ES, Stone E, Georgiou G, Manor U, Iuga A, Wahl GM, Stockwell BR, Lyssiotis CA, Olive KP (2020) Science368(6486): 85-89 › Primary publication · 32241947 (PubMed) · PMC7681911 (PubMed Central)
Gene network transitions in embryos depend upon interactions between a pioneer transcription factor and core histones. Iwafuchi M, Cuesta I, Donahue G, Takenaka N, Osipovich AB, Magnuson MA, Roder H, Seeholzer SH, Santisteban P, Zaret KS (2020) Nat Genet52(4): 418-427 › Primary publication · 32203463 (PubMed) · PMC7901023 (PubMed Central)
Long non-coding RNA enhances chondrogenesis via suppression of the interferon type II signaling pathway. Huynh NP, Gloss CC, Lorentz J, Tang R, Brunger JM, McAlinden A, Zhang B, Guilak F (2020) Elife › Primary publication · 32202492 (PubMed) · PMC7202894 (PubMed Central)
Tuft Cell Formation Reflects Epithelial Plasticity in Pancreatic Injury: Implications for Modeling Human Pancreatitis. DelGiorno KE, Naeem RF, Fang L, Chung CY, Ramos C, Luhtala N, O'Connor C, Hunter T, Manor U, Wahl GM (2020) Front Physiol : 88 › Primary publication · 32116793 (PubMed) · PMC7033634 (PubMed Central)
Uncovering cell biology in the third dimension. Robertson GL, Romero-Morales AI, Lippmann ES, Gama V (2020) Mol Biol Cell31(5): 319-323 › Primary publication · 32105584 (PubMed) · PMC7183789 (PubMed Central)
CRISPR/Cas9 engineering of albino cystinuria Type A mice. Beckermann TM, Welch RC, Williams FM, Mortlock DP, Sha F, Ikizler TA, Woodard LE, Wilson MH (2020) Genesis58(5): e23357 › Primary publication · 32078250 (PubMed) · PMC7781090 (PubMed Central)
Hyperoxia Injury in the Developing Lung Is Mediated by Mesenchymal Expression of Wnt5A. Sucre JMS, Vickers KC, Benjamin JT, Plosa EJ, Jetter CS, Cutrone A, Ransom M, Anderson Z, Sheng Q, Fensterheim BA, Ambalavanan N, Millis B, Lee E, Zijlstra A, Königshoff M, Blackwell TS, Guttentag SH (2020) Am J Respir Crit Care Med201(10): 1249-1262 › Primary publication · 32023086 (PubMed) · PMC7233334 (PubMed Central)
Mass cytometry defines distinct immune profile in germinal center B-cell lymphomas. Roussel M, Lhomme F, Roe CE, Bartkowiak T, Gravelle P, Laurent C, Fest T, Irish JM (2020) Cancer Immunol Immunother69(3): 407-420 › Primary publication · 31919622 (PubMed) · PMC7764565 (PubMed Central)
Identification and Characterization of Unique Neutralizing Antibodies to Mouse EGF Receptor. Jae Huh W, Niitsu H, Carney B, McKinley ET, Houghton JL, Coffey RJ (2020) Gastroenterology158(5): 1500-1502 › Primary publication · 31866246 (PubMed) · PMC7103561 (PubMed Central)
Discovery and Structure-Based Optimization of Potent and Selective WD Repeat Domain 5 (WDR5) Inhibitors Containing a Dihydroisoquinolinone Bicyclic Core. Tian J, Teuscher KB, Aho ER, Alvarado JR, Mills JJ, Meyers KM, Gogliotti RD, Han C, Macdonald JD, Sai J, Shaw JG, Sensintaffar JL, Zhao B, Rietz TA, Thomas LR, Payne WG, Moore WJ, Stott GM, Kondo J, Inoue M, Coffey RJ, Tansey WP, Stauffer SR, Lee T, Fesik SW (2020) J Med Chem63(2): 656-675 › Primary publication · 31858797 (PubMed) · PMC6986559 (PubMed Central)
Microtubules Regulate Localization and Availability of Insulin Granules in Pancreatic Beta Cells. Bracey KM, Ho KH, Yampolsky D, Gu G, Kaverina I, Holmes WR (2020) Biophys J118(1): 193-206 › Primary publication · 31839261 (PubMed) · PMC6950633 (PubMed Central)
Cyt-Geist: Current and Future Challenges in Cytometry: Reports of the CYTO 2019 Conference Workshops. Czechowska K, Lannigan J, Aghaeepour N, Back JB, Begum J, Behbehani G, Bispo C, Bitoun D, Fernández AB, Boova ST, Brinkman RR, Ciccolella CO, Cotleur B, Davies D, Dela Cruz GV, Del Rio-Guerra R, Des Lauriers-Cox AM, Douagi I, Dumrese C, Bonilla Escobar DL, Estevam J, Ewald C, Fossum A, Gaudillière B, Green C, Groves C, Hall C, Haque Y, Hedrick MN, Hogg K, Hsieh EWY, Irish J, Lederer J, Leipold M, Lewis-Tuffin LJ, Litwin V, Lopez P, Nasdala I, Nedbal J, Ohlsson-Wilhelm BM, Price KM, Rahman AH, Rayanki R, Rieger AM, Robinson JP, Shapiro H, Sun YS, Tang VA, Tesfa L, Telford WG, Walker R, Welsh JA, Wheeler P, Tárnok A (2019) Cytometry A95(12): 1236-1274 › Primary publication · 31833655 (PubMed)
The CK1α Activator Pyrvinium Enhances the Catalytic Efficiency (/) of CK1α. Shen C, Li B, Astudillo L, Deutscher MP, Cobb MH, Capobianco AJ, Lee E, Robbins DJ (2019) Biochemistry58(51): 5102-5106 › Primary publication · 31820934 (PubMed) · PMC6942998 (PubMed Central)
Heterogeneity within Stratified Epithelial Stem Cell Populations Maintains the Oral Mucosa in Response to Physiological Stress. Byrd KM, Piehl NC, Patel JH, Huh WJ, Sequeira I, Lough KJ, Wagner BL, Marangoni P, Watt FM, Klein OD, Coffey RJ, Williams SE (2019) Cell Stem Cell25(6): 814-829.e6 › Primary publication · 31809739 (PubMed) · PMC6925542 (PubMed Central)
Novel three-dimensional cultures provide insights into thyroid cancer behavior. Lee MA, Bergdorf KN, Phifer CJ, Jones CY, Byon SY, Sawyer LM, Bauer JA, Weiss VL (2020) Endocr Relat Cancer27(2): 111-121 › Primary publication · 31804972 (PubMed) · PMC7295136 (PubMed Central)
Sox6 as a new modulator of renin expression in the kidney. Saleem M, Hodgkinson CP, Xiao L, Gimenez-Bastida JA, Rasmussen ML, Foss J, Payne AJ, Mirotsou M, Gama V, Dzau VJ, Gomez JA (2020) Am J Physiol Renal Physiol318(2): F285-F297 › Primary publication · 31760770 (PubMed) · PMC7052657 (PubMed Central)
miR-302a Inhibits Metastasis and Cetuximab Resistance in Colorectal Cancer by Targeting NFIB and CD44. Sun L, Fang Y, Wang X, Han Y, Du F, Li C, Hu H, Liu H, Liu Q, Wang J, Liang J, Chen P, Yang H, Nie Y, Wu K, Fan D, Coffey RJ, Lu Y, Zhao X, Wang X (2019) Theranostics9(26): 8409-8425 › Primary publication · 31754405 (PubMed) · PMC6857048 (PubMed Central)
Stoichiometric optimization of Gata4, Hand2, Mef2c, and Tbx5 expression for contractile cardiomyocyte reprogramming. Zhang Z, Zhang W, Nam YJ (2019) Sci Rep9(1): 14970 › Primary publication · 31628386 (PubMed) · PMC6800441 (PubMed Central)
Inactivation of mTORC2 in macrophages is a signature of colorectal cancer that promotes tumorigenesis. Katholnig K, Schütz B, Fritsch SD, Schörghofer D, Linke M, Sukhbaatar N, Matschinger JM, Unterleuthner D, Hirtl M, Lang M, Herac M, Spittler A, Bergthaler A, Schabbauer G, Bergmann M, Dolznig H, Hengstschläger M, Magnuson MA, Mikula M, Weichhart T (2019) JCI Insight4(20) › Primary publication · 31619583 (PubMed) · PMC6824305 (PubMed Central)
Targeted mobilization of Lrig1 gastric epithelial stem cell populations by a carcinogenic type IV secretion system. Wroblewski LE, Choi E, Petersen C, Delgado AG, Piazuelo MB, Romero-Gallo J, Lantz TL, Zavros Y, Coffey RJ, Goldenring JR, Zemper AE, Peek RM (2019) Proc Natl Acad Sci U S A116(39): 19652-19658 › Primary publication · 31488717 (PubMed) · PMC6765285 (PubMed Central)
Heterogeneity of Neural Stem Cells in the Ventricular-Subventricular Zone. Rushing GV, Bollig MK, Ihrie RA (2019) Adv Exp Med Biol : 1-30 › Primary publication · 31487016 (PubMed)
Bcl2-Expressing Quiescent Type B Neural Stem Cells in the Ventricular-Subventricular Zone Are Resistant to Concurrent Temozolomide/X-Irradiation. Cameron BD, Traver G, Roland JT, Brockman AA, Dean D, Johnson L, Boyd K, Ihrie RA, Freeman ML (2019) Stem Cells37(12): 1629-1639 › Primary publication · 31430423 (PubMed) · PMC6916634 (PubMed Central)
scRNABatchQC: multi-samples quality control for single cell RNA-seq data. Liu Q, Sheng Q, Ping J, Ramirez MA, Lau KS, Coffey RJ, Shyr Y (2019) Bioinformatics35(24): 5306-5308 › Primary publication · 31373345 (PubMed) · PMC6954654 (PubMed Central)
Automated cell boundary and 3D nuclear segmentation of cells in suspension. Kesler B, Li G, Thiemicke A, Venkat R, Neuert G (2019) Sci Rep9(1): 10237 › Primary publication · 31308458 (PubMed) · PMC6629630 (PubMed Central)
Regulation of Glucose-Dependent Golgi-Derived Microtubules by cAMP/EPAC2 Promotes Secretory Vesicle Biogenesis in Pancreatic β Cells. Trogden KP, Zhu X, Lee JS, Wright CVE, Gu G, Kaverina I (2019) Curr Biol29(14): 2339-2350.e5 › Primary publication · 31303487 (PubMed) · PMC6698911 (PubMed Central)
Generating kinetic environments to study dynamic cellular processes in single cells. Thiemicke A, Jashnsaz H, Li G, Neuert G (2019) Sci Rep9(1): 10129 › Primary publication · 31300695 (PubMed) · PMC6625993 (PubMed Central)
Remodeling of mitochondrial morphology and function: an emerging hallmark of cellular reprogramming. Rastogi A, Joshi P, Contreras E, Gama V (2019) Cell Stress3(6): 181-194 › Primary publication · 31225513 (PubMed) · PMC6558935 (PubMed Central)
Metabolic consequences of cystinuria. Woodard LE, Welch RC, Veach RA, Beckermann TM, Sha F, Weinman EJ, Ikizler TA, Tischfield JA, Sahota A, Wilson MH (2019) BMC Nephrol20(1): 227 › Primary publication · 31221135 (PubMed) · PMC6585015 (PubMed Central)
Single-Cell Analyses Confirm the Critical Role of LRP6 for Wnt Signaling in APC-Deficient Cells. Cabel CR, Alizadeh E, Robbins DJ, Ahmed Y, Lee E, Thorne CA (2019) Dev Cell49(6): 827-828 › Primary publication · 31211991 (PubMed) · PMC6613640 (PubMed Central)
Multiplex RNA single molecule FISH of inducible mRNAs in single yeast cells. Li G, Neuert G (2019) Sci Data6(1): 94 › Primary publication · 31209217 (PubMed) · PMC6572782 (PubMed Central)
The Pdx1-Bound Swi/Snf Chromatin Remodeling Complex Regulates Pancreatic Progenitor Cell Proliferation and Mature Islet β-Cell Function. Spaeth JM, Liu JH, Peters D, Guo M, Osipovich AB, Mohammadi F, Roy N, Bhushan A, Magnuson MA, Hebrok M, Wright CVE, Stein R (2019) Diabetes68(9): 1806-1818 › Primary publication · 31201281 (PubMed) · PMC6702633 (PubMed Central)
Myeloid Cell-Derived HB-EGF Drives Tissue Recovery After Pancreatitis. Wen HJ, Gao S, Wang Y, Ray M, Magnuson MA, Wright CVE, Di Magliano MP, Frankel TL, Crawford HC (2019) Cell Mol Gastroenterol Hepatol8(2): 173-192 › Primary publication · 31125624 (PubMed) · PMC6661420 (PubMed Central)
Picturing Polarized Myeloid Phagocytes and Regulatory Cells by Mass Cytometry. Roussel M, Bartkowiak T, Irish JM (2019) Methods Mol Biol : 217-226 › Primary publication · 31077108 (PubMed) · PMC6886519 (PubMed Central)
Analysis of Cardiac Chamber Development During Mouse Embryogenesis Using Whole Mount Epifluorescence. Zhang Z, Nam YJ (2019) J Vis Exp(146) › Primary publication · 31058904 (PubMed) · PMC8017474 (PubMed Central)
Ensuring expression of four core cardiogenic transcription factors enhances cardiac reprogramming. Zhang Z, Zhang AD, Kim LJ, Nam YJ (2019) Sci Rep9(1): 6362 › Primary publication · 31019236 (PubMed) · PMC6482135 (PubMed Central)
Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring. Shi Y, Gao W, Lytle NK, Huang P, Yuan X, Dann AM, Ridinger-Saison M, DelGiorno KE, Antal CE, Liang G, Atkins AR, Erikson G, Sun H, Meisenhelder J, Terenziani E, Woo G, Fang L, Santisakultarm TP, Manor U, Xu R, Becerra CR, Borazanci E, Von Hoff DD, Grandgenett PM, Hollingsworth MA, Leblanc M, Umetsu SE, Collisson EA, Scadeng M, Lowy AM, Donahue TR, Reya T, Downes M, Evans RM, Wahl GM, Pawson T, Tian R, Hunter T (2019) Nature569(7754): 131-135 › Primary publication · 30996350 (PubMed) · PMC6565370 (PubMed Central)
A Synthetic Gene Circuit for Self-Regulating Delivery of Biologic Drugs in Engineered Tissues. Pferdehirt L, Ross AK, Brunger JM, Guilak F (2019) Tissue Eng Part A25(9-10): 809-820 › Primary publication · 30968743 (PubMed) · PMC6533793 (PubMed Central)
Transfer of Functional Cargo in Exomeres. Zhang Q, Higginbotham JN, Jeppesen DK, Yang YP, Li W, McKinley ET, Graves-Deal R, Ping J, Britain CM, Dorsett KA, Hartman CL, Ford DA, Allen RM, Vickers KC, Liu Q, Franklin JL, Bellis SL, Coffey RJ (2019) Cell Rep27(3): 940-954.e6 › Primary publication · 30956133 (PubMed) · PMC6559347 (PubMed Central)
Sex modifies placental gene expression in response to metabolic and inflammatory stress. Barke TL, Money KM, Du L, Serezani A, Gannon M, Mirnics K, Aronoff DM (2019) Placenta : 1-9 › Primary publication · 30955704 (PubMed) · PMC6461364 (PubMed Central)
Reassessment of Exosome Composition. Jeppesen DK, Fenix AM, Franklin JL, Higginbotham JN, Zhang Q, Zimmerman LJ, Liebler DC, Ping J, Liu Q, Evans R, Fissell WH, Patton JG, Rome LH, Burnette DT, Coffey RJ (2019) Cell177(2): 428-445.e18 › Primary publication · 30951670 (PubMed) · PMC6664447 (PubMed Central)
Protein kinase A-mediated phosphorylation of naked cuticle homolog 2 stimulates cell-surface delivery of transforming growth factor-α for epidermal growth factor receptor transactivation. Cao Z, Singh B, Li C, Markham NO, Carrington LJ, Franklin JL, Graves-Deal R, Kennedy EJ, Goldenring JR, Coffey RJ (2019) Traffic20(5): 357-368 › Primary publication · 30941853 (PubMed) · PMC6618044 (PubMed Central)
Discovering small molecules as Wnt inhibitors that promote heart regeneration and injury repair. Xie S, Fu W, Yu G, Hu X, Lai KS, Peng X, Zhou Y, Zhu X, Christov P, Sawyer L, Ni TT, Sulikowski GA, Yang Z, Lee E, Zeng C, Wang WE, Zhong TP (2020) J Mol Cell Biol12(1): 42-54 › Primary publication · 30925593 (PubMed) · PMC7259332 (PubMed Central)
Generation of Nppa-tagBFP reporter knock-in mouse line for studying cardiac chamber specification. Zhang Z, Zhang Q, Lal H, Nam YJ (2019) Genesis57(6): e23294 › Primary publication · 30920727 (PubMed) · PMC6826257 (PubMed Central)
Location-dependent maintenance of intrinsic susceptibility to mTORC1-driven tumorigenesis. Rushing GV, Brockman AA, Bollig MK, Leelatian N, Mobley BC, Irish JM, Ess KC, Fu C, Ihrie RA (2019) Life Sci Alliance2(2) › Primary publication · 30910807 (PubMed) · PMC6435042 (PubMed Central)
Location-dependent maintenance of intrinsic susceptibility to mTORC1-driven tumorigenesis. Rushing GV, Brockman AA, Bollig MK, Leelatian N, Mobley BC, Irish JM, Ess KC, Fu C, Ihrie RA (2019) Life Sci Alliance2(2) › Primary publication · 30910807 (PubMed) · PMC6435042 (PubMed Central)
Developmental regulation of Wnt signaling by Nagk and the UDP-GlcNAc salvage pathway. Neitzel LR, Spencer ZT, Nayak A, Cselenyi CS, Benchabane H, Youngblood CQ, Zouaoui A, Ng V, Stephens L, Hann T, Patton JG, Robbins D, Ahmed Y, Lee E (2019) Mech Dev : 20-31 › Primary publication · 30904594 (PubMed) · PMC6574174 (PubMed Central)
Human Germinal Center B Cells Differ from Naïve and Memory B Cells in CD40 Expression and CD40L-Induced Signaling Response. Huse K, Wogsland CE, Polikowsky HG, Diggins KE, Smeland EB, Myklebust JH, Irish JM (2019) Cytometry A95(4): 442-449 › Primary publication · 30838773 (PubMed) · PMC6711772 (PubMed Central)
Regulation of the Pancreatic Exocrine Differentiation Program and Morphogenesis by Onecut 1/Hnf6. Kropp PA, Zhu X, Gannon M (2019) Cell Mol Gastroenterol Hepatol7(4): 841-856 › Primary publication · 30831323 (PubMed) · PMC6476890 (PubMed Central)
Direct reprogramming to human nephron progenitor-like cells using inducible piggyBac transposon expression of SNAI2-EYA1-SIX1. Vanslambrouck JM, Woodard LE, Suhaimi N, Williams FM, Howden SE, Wilson SB, Lonsdale A, Er PX, Li J, Maksimovic J, Oshlack A, Wilson MH, Little MH (2019) Kidney Int95(5): 1153-1166 › Primary publication · 30827514 (PubMed) · PMC6478531 (PubMed Central)
Ventricular-Subventricular Zone Contact by Glioblastoma is Not Associated with Molecular Signatures in Bulk Tumor Data. Mistry AM, Wooten DJ, Davis LT, Mobley BC, Quaranta V, Ihrie RA (2019) Sci Rep9(1): 1842 › Primary publication · 30755636 (PubMed) · PMC6372607 (PubMed Central)
Blood vessel epicardial substance (BVES) reduces LRP6 receptor and cytoplasmic -catenin levels to modulate Wnt signaling and intestinal homeostasis. Thompson JJ, Short SP, Parang B, Brown RE, Li C, Ng VH, Saito-Diaz K, Choksi YA, Washington MK, Smith JJ, Fingleton B, Brand T, Lee E, Coffey RJ, Williams CS (2019) Carcinogenesis40(9): 1086-98 › Primary publication · 30689807 (PubMed) · PMC8067673 (PubMed Central)
Blood vessel epicardial substance (BVES) reduces LRP6 receptor and cytoplasmic -catenin levels to modulate Wnt signaling and intestinal homeostasis. Thompson JJ, Short SP, Parang B, Brown RE, Li C, Ng VH, Saito-Diaz K, Choksi YA, Washington MK, Smith JJ, Fingleton B, Brand T, Lee E, Coffey RJ, Williams CS (2019) Carcinogenesis40(9): 1086-98 › Primary publication · 30689807 (PubMed) · PMC8067673 (PubMed Central)
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Neurog3-Independent Methylation Is the Earliest Detectable Mark Distinguishing Pancreatic Progenitor Identity. Liu J, Banerjee A, Herring CA, Attalla J, Hu R, Xu Y, Shao Q, Simmons AJ, Dadi PK, Wang S, Jacobson DA, Liu B, Hodges E, Lau KS, Gu G (2019) Dev Cell48(1): 49-63.e7 › Primary publication · 30620902 (PubMed) · PMC6327977 (PubMed Central)
Active Kras Expression in Gastric Isthmal Progenitor Cells Induces Foveolar Hyperplasia but Not Metaplasia. Choi E, Means AL, Coffey RJ, Goldenring JR (2019) Cell Mol Gastroenterol Hepatol7(1): 251-253.e1 › Primary publication · 30585163 (PubMed) · PMC6305842 (PubMed Central)
A Call for Improved Reporting of Human Islet Characteristics in Research Articles. Poitout V, Satin LS, Kahn SE, Stoffers DA, Marchetti P, Gannon M, Verchere CB, Herold KC, Myers MG, Marshall SM (2019) Diabetes68(2): 239-240 › Primary publication · 30552106 (PubMed)
Beyond the message: advantages of snapshot proteomics with single-cell mass cytometry in solid tumors. Mistry AM, Greenplate AR, Ihrie RA, Irish JM (2019) FEBS J286(8): 1523-1539 › Primary publication · 30549207 (PubMed) · PMC6478512 (PubMed Central)
Beyond the message: advantages of snapshot proteomics with single-cell mass cytometry in solid tumors. Mistry AM, Greenplate AR, Ihrie RA, Irish JM (2019) FEBS J286(8): 1523-1539 › Primary publication · 30549207 (PubMed) · PMC6478512 (PubMed Central)
A call for improved reporting of human islet characteristics in research articles. Poitout V, Satin LS, Kahn SE, Stoffers DA, Marchetti P, Gannon M, Verchere CB, Herold KC, Myers MG, Marshall SM (2019) Diabetologia62(2): 209-211 › Primary publication · 30547229 (PubMed) · PMC7259467 (PubMed Central)
Transgene-associated human growth hormone expression in pancreatic β-cells impairs identification of sex-based gene expression differences. Stancill JS, Osipovich AB, Cartailler JP, Magnuson MA (2019) Am J Physiol Endocrinol Metab316(2): E196-E209 › Primary publication · 30532991 (PubMed) · PMC6397359 (PubMed Central)
Computational Immune Monitoring Reveals Abnormal Double-Negative T Cells Present across Human Tumor Types. Greenplate AR, McClanahan DD, Oberholtzer BK, Doxie DB, Roe CE, Diggins KE, Leelatian N, Rasmussen ML, Kelley MC, Gama V, Siska PJ, Rathmell JC, Ferrell PB, Johnson DB, Irish JM (2019) Cancer Immunol Res7(1): 86-99 › Primary publication · 30413431 (PubMed) · PMC6318034 (PubMed Central)
Computational Immune Monitoring Reveals Abnormal Double-Negative T Cells Present across Human Tumor Types. Greenplate AR, McClanahan DD, Oberholtzer BK, Doxie DB, Roe CE, Diggins KE, Leelatian N, Rasmussen ML, Kelley MC, Gama V, Siska PJ, Rathmell JC, Ferrell PB, Johnson DB, Irish JM (2019) Cancer Immunol Res7(1): 86-99 › Primary publication · 30413431 (PubMed) · PMC6318034 (PubMed Central)
MEK Inhibitor Reverses Metaplasia and Allows Re-Emergence of Normal Lineages in Helicobacter pylori-Infected Gerbils. Yang Q, Yasuda T, Choi E, Toyoda T, Roland JT, Uchida E, Yoshida H, Seto Y, Goldenring JR, Nomura S (2019) Gastroenterology156(3): 577-581.e4 › Primary publication · 30391471 (PubMed) · PMC6368860 (PubMed Central)
The Elegance of Sonic Hedgehog: Emerging Novel Functions for a Classic Morphogen. Garcia ADR, Han YG, Triplett JW, Farmer WT, Harwell CC, Ihrie RA (2018) J Neurosci38(44): 9338-9345 › Primary publication · 30381425 (PubMed) · PMC6209836 (PubMed Central)
Machine learning reveals chronic graft--host disease phenotypes and stratifies survival after stem cell transplant for hematologic malignancies. Gandelman JS, Byrne MT, Mistry AM, Polikowsky HG, Diggins KE, Chen H, Lee SJ, Arora M, Cutler C, Flowers M, Pidala J, Irish JM, Jagasia MH (2019) Haematologica104(1): 189-196 › Primary publication · 30237265 (PubMed) · PMC6312024 (PubMed Central)
ROCK-nmMyoII, Notch and gene-dosage link epithelial morphogenesis with cell fate in the pancreatic endocrine-progenitor niche. Bankaitis ED, Bechard ME, Gu G, Magnuson MA, Wright CVE (2018) Development145(18) › Primary publication · 30126902 (PubMed) · PMC6176929 (PubMed Central)
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